Brand Name

Dexilant {Takeda}

Generic Name

dexlansoprazole, pronounced DEX lan SOE pra zol

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Drug Guide

The information contained in the following drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.

What is Dexilant?

Dexilant is a medication that decreases the amount of acid that is produced in your stomach. In the group of medications called proton pump inhibitors, or PPIs, Dexilant helps to treat heartburn that is caused by gastroesophageal reflux disease, also known as GERD, and helps heal erosive esophagitis. Dexilant may also be used for conditions not stated in this medication guide.

Key Facts About Dexilant

Dexilant is part of a group of drugs called proton pump inhibitors, or PPIs. Dexilant can help you by decreasing the amount of acid produced in your stomach.

Your doctor may have prescribed Dexilant to help treat your symptoms from conditions involving excess stomach acids, like erosive esophagitis, or heartburn caused by GERD.

Heartburn may be confused with initial symptoms of a heart attack. You should seek emergency medical assistance if you experience chest pain or a heavy feeling, nausea, sweating, pain spreading to your arm or shoulder, or a general feeling of being ill while taking Dexilant.

If you take a proton pump inhibitor like Dexilant you may have an increased risk of bone fractures in your hips, wrists, or spine. This effect has occurred in people who have either taken this medication for a long time and at high doses, or who are older than age 50. It is not known if Dexilant is the cause of this increased risk of fractures.

Dexilant is in FDA Category B. We do not know if Dexilant can harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant if you are taking Dexilant. We do not know if Dexilant can pass into breast milk. Talk to your doctor before breast-feeding while you are taking Dexilant.

Before You Take Dexilant

If you are allergic to dexlansoprazole, you should not take Dexilant.

You should tell your doctor if you have low levels of magnesium in your blood or liver disease, as these may be reasons for you not to take Dexilant. Tell your doctor if you have either of these conditions.

Dexilant may cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is bloody or watery immediately stop taking Dexilant and call your doctor. Do not take an anti-diarrhea medication without consulting with your doctor first.

Dexilant Drug Interactions

You should inform your doctor if you are taking any of the following:

• ampicillin (Principen, Unasyn)
• atazanavir (Reyataz)
• digoxin (Lanoxin, Lanoxicaps)
• diuretics or water pills
• iron (Feosol, Mol-Iron, Fergon, Femiron)
• ketoconazole (Nizoral)
• tacrolimus (Prograf)
• warfarin (Coumadin)

Other drugs you take that are not listed may interact with Dexilant. You should tell your doctor about all of the medications you use. This includes prescription drugs, vitamins, supplements and herbal products, and over the counter medications. You should not begin taking a new medication without telling your doctor first.

Directions for Taking Dexilant

You should take Dexilant for the entire length of time your doctor has prescribed you to take it, even if your symptoms improve before you have finished your prescription. Sometimes your symptoms may improve but your condition has not yet been fully treated. You should call your doctor if your symptoms do not improve or if you experience a worsening of your symptoms while taking this medicine.

You should take each dose of Dexilant with a full glass of water, and either with or without food.

If you are being treated for heartburn as a result of GERD the typical treatment is no longer than 4 weeks. Your doctor will let you know if you need to be treated for a longer amount of time.

If you are taking Dexilant for to help heal erosive esophagitis you may need treatment for several months or longer. Your doctor will tell you the right length of treatment for your condition.

You should not break, chew or crush the delayed release capsule; you should only swallow it whole.

You may also take the Dexilant delayed-release capsule and open it to sprinkle the medication into a spoonful of applesauce or pudding to make it easier for you to swallow. You must swallow this mixture immediately, without chewing it. Do not save any unused mixture for later use, and be sure to discard the empty capsule.

Store Dexilant at room temperature, and away from both moisture and heat.

If you miss a dose of Dexilant you should attempt to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose do not take the missed dose in addition to your regular dose.

Dexilant Side Effects

If you experience any of the following adverse effects you should stop taking Dexilant and seek emergency medical help immediately.

• allergic reaction including breathing difficulties, hives or swelling of your face, lips, throat or tongue
• chest pain with pounding heartbeat
• diarrhea that is watery or bloody
• heartburn that worsens
• low magnesium signs, which include dizziness, confusion, a fast or uneven heart rate, jerking muscle movements, jittery feeling, muscle cramps, muscle weakness or limp feeling, a cough or choking feeling and seizures.
• severe stomach pain

Less serious side effects may include:

• diarrhea (mild)
• gas
• nausea
• stomach pain
• stuffy nose and sneezing with cold symptoms
• vomiting

It should be noted that this is not a complete list of possible side effects of Dexilant. You should contact your physician for a complete list and medical advice regarding these effects.

Dexilant Description and Dosing

Dexilant is available in 30mg delayed-release capsules which are opaque, blue and gray with TAP and “30” imprinted on the capsule.

Dexilant is also available in 60mg delayed-release capsules which are opaque and blue with TAP and “60” imprinted on the capsule.

Dosing of Dexilant is based on individual needs. Your doctor will determine the correct dose for your age, situation and state of health. Do not attempt to alter or change your dose without your physician’s consent.

If you think you may have overdosed on Dexilant seek emergency medical help immediately.

Ingredients in Dexilant

The active ingredient in Dexilant Delayed-Release Capsules is dexlansoprazole. Inactive ingredients include sugar spheres, magnesium carbonate, sucrose, low-substituted hydroxypropyl cellulose, titanium dioxide, hydroxypropyl cellulose, hypromellose 2910, talc, methacrylic acid copolymers, polyethylene glycol 8000, triethyl citrate, polysorbate 80, and colloidal silicon dioxide. The components of the capsule shell include the following inactive ingredients: hypromellose, carrageenan and potassium chloride. Based on the capsule shell color, blue contains FD&C Blue No. 2 Aluminum Lake; gray contains black ferric oxide; and both contain titanium dioxide.

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The information contained in this drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.