Brand Name

Dyazide {GlaxoSmithKline}

Generic Name

hydrochlorothiazide and triamterene, pronounced HYE dro klor oh THY a zide and trye AM ter een

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Drug Guide

The information contained in the following drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.

What is Dyazide?

Dyazide is a medication to treat fluid retention and hypertension, or high blood pressure in adults. Dyazide contains triamterene, which is a potassium-sparing diuretic that helps to prevent your body from absorbing too much salt and keeps your potassium levels stable. Dyazide also contains hydrochlorothiazide, which is a thiazide diuretic, or water pill, that helps your body from absorbing too much salt, which can cause fluid retention.

Dyazide may also be used for purposes not described in this medication guide.

Key Facts About Dyazide

Triamterene is a potassium-sparing diuretic which helps to prevent your body from absorbing too much salt, which keeps your potassium levels from getting too low.

Hydrochlorothiazide, which is part of Dyazide, is a thiazide diuretic, or water pill, that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Dyazide is in FDA pregnancy category C. You should not use Dyazide if you are pregnant, as we do not know if this medication will harm your unborn baby. If you become pregnant while taking Dyazide you should contact your doctor. Dyazide can pass into breast milk, so you should not breast-feed while taking this medication.

While you are taking Dyazide you should not drink alcohol. Because drinking alcohol can further lower your blood pressure you may experience an increase in certain side effects of Dyazide if you drink while taking it.

Unless your doctor has advised you to do so, you should not use potassium supplements or salt substitutes while you are taking Dyazide

Continue to use Dyazide as your doctor has directed, and be sure to get your blood pressure checked regularly.

Tell your doctor right away if you have ongoing vomiting or diarrhea, or if you are sweating more than usual while you are taking Dyazide. It is easy to become dehydrated become dehydrated while taking Dyazide, which can lead to extremely low blood pressure or a serious electrolyte imbalance.

Before You Take Dyazide

If you are allergic to hydrochlorothiazide (HCTZ, HydroDiuril, Lotensin HCT, Prinzide, Zestoretic, Ziac), triamterene (Dyrenium), sulfa drugs or penicillin you should not take Dyazide.

If you have kidney disease or are unable to urinate you should not take Dyazide.

You should inform your doctor if you have high potassium levels (hyperkalemia), if you are taking diuretics similar to triamterene, like amiloride (Midamor, Moduretic) and spironolactone (Aldactone, Aldactazide), or if you are taking potassium supplements.

If you suffer from diabetes, heart disease, cirrhosis or another liver disease, glaucoma or a breathing disorder you should tell your doctor before starting treatment with Dyazide.

Let your doctor know if you have lupus, gout, a history of kidney stones or a pancreas disorder before starting treatment with Dyazide.

Until you know how you will react to Dyazide you should avoid getting up too fast from a lying or sitting position, as you may experience dizziness. Be sure to get up slowly and steady yourself to prevent a fall, especially when you first begin your treatment with Dyazide.

You need to be aware that certain conditions can cause low blood pressure, and make the effects of Dyazide more pronounced for you. Tell your doctor right away if you experience diarrhea, heart disease, intense sweating, vomiting, dialysis, or if you are on a low salt diet or taking diuretics (water pills).

You should avoid a diet that is high in salt. Too much salt can cause your body to retain water, which can make this medication less effective.

Dyazide Drug Interactions

You should inform your doctor if you are taking any of the following:

• ACE inhibitor such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril) and ramipril (Altace)
• allopurinol (Zyloprim)
• amphotericin B (Amphotec, AmBisome, Abelcet)
• aspirin
• celecoxib (Celebrex)
• colchicine (Colcrys)
• diabetes medication (oral) or insulin
• diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze)
• diuretics or water pills like amiloride (Midamor), bumetanide (Bumex), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Lopressor HCT, Vasoretic, Zestoretic), spironolactone (Aldactone) and torsemide (Demadex)
• ibuprofen (Advil, Motrin)
• indomethacin (Indocin), meloxicam (Mobic)
• laxatives
• lithium (Eskalith, Lithobid, Lithonate)
• meloxicam (Mobic)
• methenamine (Hiprex, Mandelamine, Urex)
• naproxen (Aleve, Naprosyn, Naprelan, Treximet)
• probenecid (Benemid)
• steroids (prednisone)
• warfarin (Coumadin)

Other drugs you take that are not listed may interact with Dyazide. You should tell your doctor about all of the medications you use. This includes prescription drugs, vitamins, supplements and herbal products, and over the counter medications. You should not begin taking a new medication without telling your doctor first.

Directions for Taking Dyazide

You should take Dyazide exactly your doctor has told you to. It is important that you do not take Dyazide in larger or smaller amounts, or for longer or shorter than recommended. Follow the directions on your prescription label and follow any dose changes carefully if your doctor instructs you to change your dose.

Dyazide is most effective if it is taken at the same time every day, and with a full (8oz) glass of water.

Dyazide can be taken with or without food.

You may need to take Dyazide on a long-term basis for the treatment of high blood pressure. It is important that you follow up with your doctor on a regular basis to be sure that Dyazide is helping your condition and not causing you to have any adverse or harmful effects.

Dyazide should be stored at room temperature, and away from both moisture and heat.

If you miss a dose of Dyazide you should attempt to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, or if your next dose is less than 12 hours away you should skip the dose you missed.

Dyazide Side Effects

If you experience any of the following adverse effects you should stop taking Dyazide and seek emergency medical help immediately.

• allergic reaction including hives, swelling in your face, lips, throat or tongue and trouble breathing
• easy bruising or unusual bleeding, such as from your mouth, nose, rectum or vagina
• feeling faint
• high potassium symptoms, such as a slow heart rate, weak pulse, muscle weakness, or a tingly feeling
• jaundice or yellowing of your eyes or skin
• fast, slow or uneven heartbeats
• low potassium symptoms, like confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness and a limp feeling
• rash that is red, severe, blistering and peeling along with a headache, sore throat and fever
• red or purple pinpoint spots under your skin or a patchy skin color with a red butterfly-shaped skin rash over your cheeks and nose, which worsens in sunlight
• stomach pain (especially upper stomach) that spreads to your back with nausea and vomiting
• swelling and rapid weight gain
• urinating less than normal or not at all
• vision problems or eye pain

Less serious side effects of Dyazide may include:

• blurry vision
• constipation
• diarrhea
• dizziness
• dry mouth
• headache
• nausea
• rash (mild)

It should be noted that this is not a complete list of possible side effects of Dyazide. You should contact your physician for a complete list and medical advice regarding these effects.

Dyazide Description and Dosing

Dyazide is available in a capsule form in a dose of 25 mg/37.5 mg. The capsules have an opaque red cap and opaque white body, and contain hydrochlorothiazide 25 mg and triamterene 37.5 mg. The capsules are imprinted with the product name Dyazide and SB.

Dyazide is also available in a tablet form in a dose of 25mg/50mg.

Consult with your doctor for specific dosing pertaining to you. Do not attempt to alter or change your dose of Dyazide without your physician’s consent.

If you suspect that you have overdosed with Dyazide you should seek emergency help immediately.

Ingredients in Dyazide

Dyazide contains the active ingredients hydrochlorothiazide and triamterene. Inactive ingredients include benzyl alcohol, cetylpyridinium chloride, D&C Red No. 33, FD&C Yellow No. 6, gelatin, glycine, lactose, magnesium stearate, microcrystalline cellulose, povidone, polysorbate 80, sodium starch glycolate, titanium dioxide, and trace amounts of other inactive ingredients.

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The information contained in this drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.