Brand Name

Altace {King Pharmaceuticals}

Generic Name

ramipril, pronounced RAM i pril

---

Drug Guide

The information contained in the following drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.

What is Altace?

Altace is a medication to treat hypertension, or high blood pressure, and is in a group ofmedications called angiotensin converting enzyme inhibitors {ACE inhibitors}. You may also beprescribed Altace to treat congestive heart failure or to lower your risk of death if you havehad a heart attack.

Altace may also be used for purposes not described in this medication guide.

Key Facts About Altace

Altace is in FDA pregnancy category D. You should not use Altace if you are pregnant. If youbecome pregnant while taking Altace you should stop taking this medication and contact yourdoctor right away. Altace may cause injury or death to an unborn baby if taken during your secondor third trimester. You should be sure to use effective birth control while taking Altace.

While you are taking Altace you should not drink alcohol. Because drinking alcohol can furtherlower your blood pressure you may experience an increase in certain side effects of Altace if youdrink while taking it.

Unless your doctor has advised you to do so, you should not use potassium supplements or saltsubstitutes while you are taking Altace.

Until you know how you will react to Altace you should avoid getting up too fast from a lyingor sitting position, as you may experience dizziness. Be sure to get up slowly and steadyyourself to prevent a fall, especially when you first begin your treatment with Altace.

If you suffer from vomiting, diarrhea, or heavy sweating you can easily become dehydratedwhile taking Altace. This can lead to very low blood pressure, electrolyte disorders, or kidneyfailure. You should tell your doctor if you suffer from these symptoms while taking Altace, andbe certain to drink plenty of water each day while you are taking this medication.

Continue to use Altace as your doctor has directed, and be sure to get your blood pressurechecked regularly.

Before You Take Altace

If you are allergic to lisinopril, or any other ACE inhibitor, like benazepril (Lotensin),fosinopril (Monopril), enalapril (Vasotec), moexipril (Univasc), perindopril (Aceon), quinapril(Accupril), ramipril (Altace), or trandolapril (Mavik) you should not take Altace.

If you are taking telmisartan (Micardis) you should not take Altace.

You should tell your doctor if you have ever had a severe allergic reaction to anything beforetaking Altace.

You should inform your doctor if you have liver disease, kidney disease, heart disease orcongestive heart failure before taking Altace.

If you have diabetes you should tell your doctor before starting treatment with Altace.

Let your doctor know if you have a connective tissue disease like Marfan syndrome, Sjogren’ssyndrome, lupus, scleroderma, or rheumatoid arthritis before taking Altace.

Altace Drug Interactions

You should inform your doctor if you are taking any of the following:

• aspirin
• diuretics or water pills like amiloride (Midamor, Moduretic), spironolactone (Aldactone,Aldactazide), or triamterene (Dyrenium, Maxzide, Dyazide)
• gold injections to treat arthritis
• lithium (Lithobid, Eskalith)
• NSAIDs (non-steroidal anti-inflammatory drugs) like ibuprofen (Advil, Motrin), naproxen(Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia,Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin) and meloxicam(Mobic)
• potassium supplements like K-Dur or Klor-Con
• salt substitutes that contain potassium

Other drugs you take that are not listed may interact with Altace. You should tell your doctorabout all of the medications you use. This includes prescription drugs, vitamins, supplements andherbal products, and over the counter medications. You should not begin taking a new medicationwithout telling your doctor first.

Directions for Taking Altace

You should take Altace exactly as directed by your doctor. It is important that you do nottake Altace in larger or smaller amounts, or for longer or shorter than recommended. Follow thedirections on your prescription label and follow any dosage changes carefully if your doctorinstructs you to change your dose.

Altace can be taken with or without food.

You should swallow the Altace capsule whole or you may open the capsule and sprinkle themedicine into a half-cup (4 ounces) of water, apple juice, or applesauce to make swallowing iteasier. Be sure to swallow without chewing. This mixture can be store for up to 24 hours at roomtemperature or up to 48 hours in a refrigerator. Do not freeze the mixture.

You may need to take Altace on a long-term basis for the treatment of high blood pressure. Itis important that you follow up with your doctor on a regular basis to be sure that Altace ishelping your condition and not causing you to have any adverse or harmful effects.

Altace should be stored at room temperature, and away from both moisture and heat.

If you miss a dose of Altace you should attempt to take the missed dose as soon as youremember. However, if it is almost time for your next scheduled dose, or if your next dose isless than 12 hours away you should skip the dose you missed.

Altace Side Effects

If you experience any of the following adverse effects you should stop taking Altace and seekemergency medical help immediately.

• allergic reaction including breathing difficulties, hives and swelling of your face, lips,throat or tongue
• chest pain
• confusion
• dark urine
• dry mouth with excessive thirst
• easy bruising or bleeding
• faint feeling and paleness
• fever with chills, body aches and flu symptoms
• heartbeats which are fast, pounding or uneven
• high potassium signs, with symptoms like a slow heart rate, weak pulse, muscle weakness or atingly feeling
• jaundice or a yellowing of your eyes and skin
• sores in your mouth or throat
• swelling with rapid weight gain
• urinary abnormalities, such as urinating less often or not at all

Less serious side effects of Altace may include:

• appetite loss or loss of taste sensation
• cough
• dizziness or spinning sensation
• drowsiness
• headache
• nausea
• vomiting

It should be noted that this is not a complete list of possible side effects of Altace. Youshould contact your physician for a complete list and medical advice regarding these effects.

Altace Description and Dosing

Altace is available hard gelatin capsules containing 1.25 mg, 2.5 mg, 5 mg, and 10 mg oframipril. The 1.25 mg capsule is yellow, the 2.5 mg capsule is orange, the 5 mg capsule is redand the 10 mg capsule is blue.

Your doctor will prescribe the correct dose of Altace for you. Do not alter or change yourdose of Altace without your physician’s consent.

If you suspect that you have overdosed with Altace you should seek emergency helpimmediately.

Ingredients in Altace

Altace contains ramipril as the active ingredient. Inactive ingredients are regelatinizedstarch NF, gelatin, and titanium dioxide. The 1.25 mg capsule shell contains yellow iron oxide,the 2.5 mg capsule shell contains D&C yellow #10 and FD&C red #40, the 5 mg capsule shellcontains FD&C blue #1 and FD&C red #40, and the 10 mg capsule shell contains FD&Cblue #1.

Back to Top

The information contained in this drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.