Brand Name

Sporanox {Janssen}

Generic Name

itraconazole, pronounced IT ra KON a zole

---

Drug Guide

The information contained in the following drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.

What is Sporanox?

Sporanox is an antifungal medication. You may be prescribed Sporanox to treat an infection caused by fungus. Fungal infections can occur in the fingernails, lungs, mouth, throat or toenails.

Sporanox may also be used for reasons not stated in this medication guide.

Key Facts About Sporanox

If you take Sporanox with certain medications,dangerous side effects may occur. Tell your doctor if you take cisapride, dihydroergotamine, dofetilide, ergonovine, ergotamine, felodipine, lovastatin, methylergonovine, methadone, midazolam, nisoldipine, pimozide, quinidine, simvastatin or triazolam.

Sporanox is in FDA pregnancy category C. Sporanox is not known to harm an unborn baby. You should tell your doctor if you are pregnant, or if you plan to become pregnant before you start to take Sporanox.

You should not use Sporanox without telling your doctor if you are breastfeeding a baby, as we know that Sporanox passes into breast milk.

You must take Sporanox for the full length of time that your doctor has prescribed. Do not stop taking Sporanox because you think you are better without talking to your doctor first.

Before You Take Sporanox

If you are allergic to itraconazole or medications like Sporanox like fluconazole or ketoconazole you should not take Sporanox.

Do not take Sporanox if you are pregnant or think you may become pregnant.

If you have had congestive heart failure you should not take Sporanox.

Tell your doctor if you have heart disease, a heart rhythm disorder or a personal or family history of Long QT syndrome before starting treatment with Sporanox.

Let your doctor know if you have circulation problems, a history of stroke, chronic obstructive pulmonary disease (COPD) or another breathing disorder before taking Sporanox.

If you have kidney disease, cirrhosis of the liver, liver disease or cystic fibrosis you should inform your doctor before beginning treatment with Sporanox.

If you take Sporanox with certain medicationsdangerous side effects may occur. Tell your doctor if you take cisapride, dihydroergotamine, dofetilide, ergonovine, ergotamine, felodipine, lovastatin, methylergonovine, methadone, midazolam, nisoldipine, pimozide, quinidine, simvastatin or triazolam.

While you are taking Sporanox take care to avoid taking antacids or stomach acid reducers, like Tagamet or Pepcid, within 1 hour before or 2 hours after you take this medication. Acid reducers may make it harder for your body to absorb Sporanox.

Sporanox Drug Interactions

You should inform your doctor if you are taking any of the following:

• antibiotics like clarithromycin, erythromycin and telithromycin
• antidepressants like nefazodone, paroxetine and sertraline (Zoloft)
• antifungal medications like clotrimazole, ketoconazole and voriconazole
• barbiturates like ambarbital, butabarbital, mephobarbital, secobarbital and phenobarbital
• blood pressure and heart medications like amlodipine, diltiazem, nifedipine and verapamil
• blood thinners like warfarin (Coumadin)
• cancer medications
• cholesterol medications like atorvastatin (Lipitor)
• cyclosporine
• diabetes medications (oral)
• digitalis
• digoxin
• disopyramide
• fentanyl
• HIV/AIDS medications like atazanavir, delavirdine, efavirenz, etravirine, indinavir,
  nelfinavir, nevirapine, ritonavir and saquinavir
• isoniazid
• rifabutin
• rifampin
• sedatives like alprazolam and diazepam (Valium)
• sirolimus
• seizure medications like carbamazepine, felbamate, oxcarbazepine, phenytoin and primidone
• tacrolimus

Other drugs you take that are not listed may interact with Sporanox. You should tell your doctor about all of the medications you use. This includes prescription drugs, vitamins, supplements and herbal products, and over the counter medications. You should not begin taking a new medication without telling your doctor first.

Directions for Taking Sporanox

You should take Sporanox exactly as directed by your doctor. It is important that you do not take Sporanox in larger or smaller amounts, or for longer or shorter than recommended. Follow the directions on your prescription label and follow any dose changes carefully if your doctor instructs you to change your dose.

Take care to vigorously swish the Sporanox Oral Solution in your mouth, 10 mL at a time, for several seconds and then swallow it.

You should use the special dose measuring device to measure the Sporanox Oral Solution, such as a special cup or spoon. If you do not have a dose measuring device your doctor or pharmacist can give one to you.

While you are taking Sporanox take care to avoid taking antacids or stomach acid reducers, like Tagamet or Pepcid, within 1 hour before or 2 hours after you take this medication. Acid reducers may make it harder for your body to absorb Sporanox.

You must take Sporanox for the full amount of time your doctor has prescribed for you to take it.

Sporanox needs to be stored at room temperature, and away from light, moisture and heat. Keep your bottle tightly closed when you are not using it. Do not freeze Sporanox.

If you miss a dose of Sporanox you should attempt to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose do not take the missed dose in addition to your regular dose.

Sporanox Side Effects

If you experience any of the following adverse effects you should stop taking Sporanox and seek emergency medical help immediately:

• allergic reactions such as breathing difficulties, hives, or swelling of your face, lips, throat or tongue
• blurred vision
• chest pain and shortness of breath, even with mild exertion
• double vision
• ringing in ear or trouble hearing
• fever
• jaundice with symptoms like clay- colored stools, itching, dark urine, appetite loss, weakness and nausea
• loss of bladder control
• numbness and tingling
• pain or burning when you urinate
• shortness of breath
• swelling with rapid weight gain
• upper stomach pain that is severe and spreads to your back with nausea, vomiting and a fast heartbeat

Less serious side effects of Sporanox may include:

• bloating
• cold symptoms, like a runny nose
• constipation
• diarrhea
• dizziness
• headache
• joint pain
• muscle pain
• nausea
• mild rash with itching
• unpleasant taste in your mouth
• upset stomach
• mild vomiting
• weakness

It should be noted that this is not a complete list of possible side effects of Sporanox. You should contact your physician for a complete list and medical advice regarding these effects.

Sporanox Description and Dosing

Sporanox Oral Solution is indicated for the treatment of esophageal and oropharyngeal candidiasis. The Sporanox Oral Solution is available in 150 mL amber glass bottles which contain 10 mg of itraconazole per mL. Sporanox Oral Solution is clear and yellowish in color.

You should consult your doctor for specific dosing pertaining to you. Do not attempt to alter or change your dose without your physician’s consent.

If you suspect that you have overdosed with Sporanox you should seek emergency help immediately.

Ingredients in Sporanox

Sporanox is comprised of the main ingredient itraconazole. The Oral Solution also contains the inactive ingredients hydrochloric acid, propylene glycol, purified water, sodium hydroxide, sodium saccharin, sorbitol, cherry flavor 1, cherry flavor 2 and caramel flavor.

Back to Top

The information contained in this drug guide is intended as an educational resource only. This guide is not exhaustive and does not contain all available information about this drug.This guide is not intended as medical advice for individual conditions or treatment.

The information provided in this guide does not replace the need for the advice and services of medical professionals or the need for medical examination. Always talk to your physician or pharmacist before taking any prescription medication or over the counter drugs (including any supplements) or before making any changes to your treatment. Only your doctor, nurse or pharmacist can provide you with safe and effective advice regarding your drug treatment.

The use of the information in this guide is at your sole risk. This information is provided "AS IS" with no warranties to accuracy or timeliness.

**All trademarks and registered trademarks are the property of their respective owners.